Extreme shifts in mood, energy, and behavior are characteristic of bipolar disorder (previously termed “manic-depression”). Individuals with this disorder fluctuate between feeling especially energetic and “up” (known as manic) and “down” or depressive cycles.

Manic phases may include feeling extremely good and even euphoric, with little need for sleep, racing, easily-distractible thoughts expressed in rapid speech, and engaging in spending sprees or other unusual behavior.

Depressive cycles can include feelings of sadness, anxiety, emptiness, hopelessness, worthlessness, and guilt. Activities that were once enjoyable are no longer interesting or pleasurable, and eating and sleeping habits often change. Extreme depressive cycles include thoughts of suicide or death.

Individuals with bipolar disorder may notice only some of these symptoms in either the “up” or “down” phases; it’s not necessary to have experienced all of them to be diagnosed as bipolar.

Artemis Institute for Clinical Research conducts clinical trials of investigative medications for the treatment of bipolar disorder. Qualified people participating in a trial may be eligible to receive financial compensation for time and travel, study-related medical and psychological evaluations, and the investigative study medication at no cost.

If you have experienced some or all of the symptoms described and would like to volunteer for a study, or if you know someone with bipolar disorder who may want to volunteer, please send us your request using the Join a Study form, or call us toll-free at 855-DoStudies (855.367.8834).

Application for Bipolar Disorder Clinical Research Study

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